Lea Seydoux and Lindsay Wagner are part of the Death Stranding cast, a new gameplay trailer revealed at Sony's E3 2018 press conference.
The trailer began with a tease from the baby then transitioned into a conversation between Norman Reedus' character, Sam, and an unnamed woman. Sam was asked to work for her, but said he just made deliveries. He was then shown walkthrough through various environments and eventually shown talking with Lea Seydoux.
"Give me your hand in life" was a phrase used often between scenes.